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  • <div>The architecture of the lithosphere controls the distribution of thermal, compositional and rheological interfaces. It therefore plays a fundamental role in modulating key ore-forming processes including the generation, transport, fractionation, and contamination of melts.&nbsp;Recognition of its importance has led to renewed efforts in recent years to incorporate constraints on lithospheric structure into the targeting of prospective regions for mineral exploration. One example is a suggested relationship between the genesis of porphyry copper deposits – known to be associated with evolved, silica-rich magmas – and the thickness of the crust.&nbsp;Here, using a new compilation of spot measurements, we explore the utility of crustal thickness as an exploration tool for porphyry copper deposits.</div> This Abstract was submitted & presented at the 2022 American Geophysical Union (AGU) Fall Meeting 12-16 December (https://www.agu.org/Fall-Meeting-2022)